Antibody Characterization

of recombinant monoclonal antibodies

Do you need sequence confirmation of a monoclonal ab?
Are you tired of waiting months for analysis results?

We provide optimized IgG analyses for early discovery, process development, and pharmacokinetics/pharmadynamics of monoclonal antibody-based pharmaceuticals.

Our antibody analyses include:

• Heavy and light chain Mw determination by mass spectrometry
• Peptide mapping by mass spectrometry of heavy and light chain
• N- and C-terminal sequencing of heavy and light chain by MALDI ISD
• Edman N-terminal sequencing
• CDR sequencing of variable complementary determining regions
• 1D SDS PAGE and 2D PAGE electrophoresis
• Post translational modification analysis; deamidation, oxidation, pyroglutamate, N-glycosylation
• Antibody quantification assay by LC MS/MS
• Host Cell Protein (HCP) identification assay