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Molecular weight analysis of mAb

Determination of exact molecular weight of intact and reduced monoclonal antibody

Do you want to confirm your monoclonal antibody by molecular weight analysis?

We can determine the exact weight of your intact antibody. We reduce the antibody into fragments of heavy chain and light chain. We then determine the exact molecular weight of each of these. We also offer to deglycosylate your antibody. The exact molecular weight of the deglycosylated form can then be determined.

Our service includes:

  • Exact mass of intact mAb determined by UV-LC ESI MS.
  • Reduction of mAb into heavy chain and light chain.
  • Exact mass of heavy chain and light chain by UV-LC ESI MS.
  • Comparison with theoretical masses.
  • Optional removal of N-glycosylations and mass of deglysocylated form.

We offer a range of other monoclonal antibody characterization services. For example: • Disulfide analysis.Peptide mapping of antibodies. • De-novo sequencing of antibodies.

If you have any questions, please send us a project proposal request.

Services/Products
Protein analysis by Alphalyse

Exact molecular weight of intact mAb

  • Exact MW of intact antibody
  • Reduction of antibody
  • Exact MW of heavy and light chain
  • Comparison with the expected masses

$2,300.00

World Class Service
Quality analysis, presented in easy-to-understand reports
Info / Order
Request quote
Protein analysis by Alphalyse

Exact molecular weight of mAb including deglycosylation

  • Exact MW of intact antibody
  • Reduction and deglycosylation of antibody
  • Exact MW of heavy and light chain and deglycosylated forms
  • Comparison with the expected masses

$2,700.00

World Class Service
Quality analysis, presented in easy-to-understand reports
Info / Order
Request quote
Order analysis now
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