GTP Technology develops a massive number of high-quality mAbs with Alphalyse’s LC-MS analysis for characterization. This high-throughput LC-MS method allows GTP to reduce their development and production time.
Gene-to-Proteins Technology (GTP) is a France-based CDMO that specializes in custom recombinant protein and process development services for biopharmaceutical companies. GTP provide their customers with services that include expression, development and purification optimization of protein-based biologics.
Since GTP produces a high number of antibodies within a short time, they need a high-throughput method for rapid quality review. Therefore, Alphalyse supplies GTP with antibody characterization on a continuing basis.
By applying state-of-the-art LC-MS setups, GTP quickly receive elaborate results. Specifically, the mAb characterization package determines the exact mass of intact antibody, of heavy and light chains, and of deglycosylated forms for verification of the expected amino acid sequences.