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Antibody Characterization

Structural characterization of antibodies, ADC's and biosimilars

Are you looking for a professional antibody characterization service?

Alphalyse offers a whole range of analytical services for structural antibody characterization of monoclonal antibodies. We perform our tests according to the ICH Q6B guidelines – Test Procedures and Acceptance Criteria for Biotechnological/Biological Products.

Our optimized analytical antibody characterization services are suitable for monoclonal antibodies, antibody-drug-conjugates and also for antibody biosimilars.

You can choose and combine your preferred analysis package from the following services:

Molecular weight of mAb.. (read more)
We determine the exact molecular weight of both intact and reduced monoclonal antibodies.

Disulfide analysis of mAb.. (read more)
We determine the number and also the position of disulfide bridges in monoclonal antibodies.

Peptide mapping of mAb.. (read more)
We confirm the theoretical amino acid sequence of your monoclonal antibodies by peptide mapping.

De-novo sequencing of mAb.. (read more)
We determine the exact amino acid sequence of your monoclonal antibodies by de-novo sequencing.

Edman sequencing of mAb.. (read more)
We can sequence up to 30 residues from the N-termini of your antibody by N-terminal Edman degradation.

Antibody-drug conjugates.. (read more)
We determine the exact distribution of drug-to-antibody ratio (DAR). In addition we find the exact attachment site(s) of the drug molecule.

Send us your project description so we can design a service package that meets your needs.


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