Are you looking for a professional antibody characterization service?
Alphalyse offers a whole range of analytical services for structural antibody characterization of monoclonal antibodies. We perform our tests according to the ICH Q6B guidelines – Test Procedures and Acceptance Criteria for Biotechnological/Biological Products.
Our optimized analytical antibody characterization services are suitable for monoclonal antibodies, antibody-drug-conjugates and also for antibody biosimilars.
You can choose and combine your preferred analysis package from the following services:
Molecular weight of mAb >
We determine the exact molecular weight of both intact and reduced monoclonal antibodies.
Disulfide analysis of mAb >
We determine the number and also the position of disulfide bridges in monoclonal antibodies.
Peptide mapping of mAb >
We confirm the theoretical amino acid sequence of your monoclonal antibodies by peptide mapping.
De-novo sequencing of mAb >
We determine the exact amino acid sequence of your monoclonal antibodies by de-novo sequencing.
Edman sequencing of mAb >
We can sequence up to 30 residues from the N-termini of your antibody by N-terminal Edman degradation.
Antibody-drug conjugates >
We determine the exact distribution of drug-to-antibody ratio (DAR). In addition we find the exact attachment site(s) of the drug molecule.