Do you want to confirm your monoclonal antibody by molecular weight analysis?
We can determine the exact weight of your intact antibody. First, we reduce the antibody into fragments of heavy chain and light chain. We then determine the exact molecular weight of each of these. We also offer to deglycosylate your antibody. The exact molecular weight of the deglycosylated form can then be determined.
Our service includes:
- Exact mass of intact mAb determined by UV-LC ESI MS.
- Reduction of mAb into heavy chain and light chain.
- Exact mass of heavy chain and light chain by UV-LC ESI MS.
- Comparison with theoretical masses.
- Optional removal of N-glycosylations and mass of deglysocylated form.
We also offer a range of other monoclonal antibody characterization services. For example: • Disulfide analysis. • Peptide mapping of antibodies. • De-novo sequencing of antibodies • Glycosylation analysis.
If you have any questions, please send us a project proposal request.