Molecular weight determination

Molecular weight determination of peptides, proteins, and antibodies is strong evidence for the correct expression of specific proteins. It is also a fast analysis to verify the purity and map a wide range of post-translation modifications and eventual degradation products.

With our setup, you can access top-of-the-line mass spectrometry instruments that provide very accurate molecular weight (MW) of proteins and antibodies. We can perform the analysis on a few µg of protein. 

Molecular weight determination can be conducted both before and after protein reduction. You can also use it before and after de-glycosylation and even after specific digest forming sub-units.

Would you like to combine it with other services related to molecular weight determination?

Molecular weight determination is often essential to a comprehensive protein characterization project. When bundled with peptide mapping, host cell protein analysis, and amino acid analysis, it forms an overview of the protein stability, function, and purity.