See how Rikke Lund’s team helps with removal of host cell protein contaminants from recombinant protein with the use of mass spectrometry.
In this short video Rikke gives examples of customer results.
The host cell protein analysis provides the customer with both identity and quantity of individual HCPs. This makes it possible to compare and identify differences of various production batches.
In addition, the method is a great tool for process development. Here it gives detailed knowledge about amounts of individual host cell proteins. Therefore, it is easy to eliminate them during the downstream purification – and LC-MS/MS is thus a great tool for host cell protein removal.
You can find more information about the LC-M/MS method in this blog post on SWATH analysis by mass spectrometry. Or check out this page to can learn more about our analysis service and how to follow hcp levels.