Do you need to determine the liquid chromatographic pattern of the proteins in your drug sample?
Many laboratories use Size Exclusion (SEC), Ion Exchange (IEX) and Reversed-Phase chromatography (RP HPLC) as part of a their protein characterization analysis. The chromatography may leave you with questions about the identity of specific peaks and shoulders in your chromatogram. However, a molecular weight analysis of the peaks by mass spectrometry will often identify the molecule.
Our services include:
- Standard or customized HPLC analysis of your sample
- Fractions collected for further analysis
- Can be combined with ESI-MS analysis for mass determination of each peak, N-terminal Edman Sequencing and peptide mapping analysis
Need to set up a custom HPLC analysis method?
We can also develop a customized method meeting your specific needs. For instance an in-house method, which you want us to set up in our laboratory. We can combine it with high resolution Mw determination by mass spectrometry.
You can send us a request so we can meet your specific needs.