Adenovira - Gene therapy analysis

Why measure process-related impurities in gene therapies with LC-MS?

Question: Can I use mass spectrometry to document process-related impurities? I work in a biopharmaceutical company developing a gene therapy product...

Dec 2. 2020 | Ejvind Mørtz |
ELISA coverage

Can I use commercial HCP ELISA kits in clinical trial documentation?

Question: Does our generic HCP ELISA kit have sufficient coverage? My company uses a commercial HCP ELISA kit for host cell protein...

Jul 10. 2019 | Ejvind Mørtz |

What are Host Cell Proteins (HCPs)?

Question: What are Host Cell Proteins and how are they measured? I recently met the term Host Cell Proteins (HCPs) in relation...

Jan 10. 2019 | Ejvind Mørtz |
1000 proteins quantified in e. coli mock lysate - HCP

Simple way to perform label-free quantification of Host Cell Proteins

Question: How can I improve label-free quantification of HCP? I find it difficult to get an accurate label-free quantification of Host Cell...

Jun 25. 2018 | Ejvind Mørtz |

How do ‘Jackpot HCPs’ and a ‘Lucky Goat’ influence my ELISA results?

Question: Why do HPC ELISAs give different results? I tested two different HCP ELISA kits on my biopharmaceutical. Why do they give...

May 28. 2018 | Anette Draborg |
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