Alphalyse - Protein Analysis Service

Your ProfessionalContract Analysis Partner for developing superior biologics

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Phone: +45 6310 6500 US: (650) 543-3193
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Live webinar
Product-Specific HCP Profiling of Advanced Therapies and Vaccines

In these live broadcasts, leading cell and gene therapy, phage, and vaccine developers present approaches to the CMC challenges.

Learn more and see the full program

On-demand webinar
Analyzing vaccine purity - without an HCP ELISA

Are you struggling to document that your downstream process consistently produces a safe product? In this webinar, you will learn how to quickly measure and compare residual protein in any type of vaccine.

Explore how to improve vaccine purity using LC-MS

On-demand webinar
MS-based analysis under GMP

Now you can rethink your HCP assay strategy with mass spectrometry (MS)-based HCP analysis available from a GMP-certified lab. It is ideal when there is no sufficient generic ELISA for your cell line – or when the time to develop a process-specific ELISA is limited, e.g., for phase 2 and 3 clinical trials.

Learn more and sign up

Focus on
Residual protein analysis in cell and gene therapies

In CMC development, one of the biggest challenges is ensuring and documenting that the downstream process consistently produces a safe product. However, the complex bioproduction of of cell therapies, gene teherapies and viral vaccines produce a diverse range of proteins, which we must monitor for consistency.

Learn more about the challenges and solutions

Focus on
HCP analysis using mass spectrometry (LC-MS)

We offer a broad range of mass spectrometry based analyses of Host Cell Proteins that can be applied from the onset of your project and throughout the development phase. Apply the analysis on its own or in combination with ELISA assays for detailed analysis of process-related impurities in your biologic

Explore our HCP analysis services

Free tool
GPMAW lite

GPMAW lite is a free protein bioinformatics tool with which you can perform basic calculations, like molar mass conversion. Use it on any protein amino acid sequence and get info about pI, MW and amino acid composition

Start GPMAW lite

In good company

For the past 20 years we have provided detailed protein
ms analysis service to customers all over the world. Among our customers you find both small and large scale biotech companies
and 8 of the top-10 pharmaceutical companies.

Professional protein analysis service for the biopharma industry

Since 2002 Alphalyse has provided standard and custom protein analysis services to the biopharmaceutical industry, biotech companies and universities worldwide. Over the years, we have serviced thousands of customers from our protein analysis lab and offices in Denmark and the USA.

Alphalyse is a contract research laboratory (CRO), proficient in protein chemistry, mass spectrometry and bioinformatics. Our team of dedicated and highly skilled protein scientists is committed to helping you bring your processes forward, by analyzing biopharmaceutical proteins using top-of-the-line equipment.

As a CRO, we have obtained a lot of knowledge through our many customer projects

Alphalyse Video

Frequently asked questions

[sc_fs_multi_faq headline-0=”h2″ question-0=”Which analyses should be included in biopharmaceutical protein analysis?” answer-0=”For approval by regulatory authorities, typically methods like intact mass, peptide mapping, N-terminal sequencing, and impurity analysis must be carried out to ensure proper documentation. This is both to verify the protein sequence, assess PTMs, evaluate the purity (and identify harmful protein residuals), as well as establish production consistency.” image-0=”” headline-1=”h2″ question-1=”Where can I get more information about Host Cell Protein analysis by mass spectrometry?” answer-1=”A great place to start is a webinar. You can find on-demand webinars at ” image-1=”” headline-2=”h2″ question-2=”What makes Alphalyse experts in HCP analysis?” answer-2=”Since 2002 our protein analysis lab has conducted thousands of analysis projects. Our first article on the use of mass spectrometry for the characterization of proteins was published in 2008. Since then we have developed a unique method of analyzing HCPs using mass spectrometry, and we have now successfully completed more than 150 HCP customer projects.” image-2=”” count=”3″ html=”true” css_class=””]

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