Don't rely solely on ELISA for HCP analysis

Get a detailed Host Cell Protein evaluation – to speed up your process

World's most experienced HCP analysis lab

Get started with a short telephone meeting:

Let’s discuss how you can benefit from adding mass spectrometry data to your HCP evaluation.

For instance, how you can use the data to clean up impurities, minimize development time, and improve your HCP documentation.

Get input for your specific project; e.g.

Optimization of your bioprocess
Analysis and comparison of clinical batches
Quantification of specific HCPs
Coverage analysis for your ELISA
Detection of process-related or HCP residuals
Comparison of biosimilars and originator

Are you a Manager or Lead Scientist in Analytical or Process Development?

Then you might be unsure of:

The exact content of your process and product samples?
The stability and structure of your biologic?
How to improve and reduce your tiresome purification steps?

Or maybe you simply need a second look on your Host Cell Protein analysis?

Book a meeting with one of our HCP consultants to get input for your project

After the meeting, you will have:

In-depth knowledge of how Mass Spectrometry complement ELISA

An overview of the services that fit your project

The possibility to receive a customized project proposal

What have others gained from working with us?

So far we have completed 60+ succesful Host Cell Protein projects based on Mass Spectrometry (MS)

Alphalyse's HCP analysis saved us the development of an ELISA assay that may not have worked anyway

Statens Serum Institut (SSI), Denmark Max Kristiansen, Special Consultant Assay Development

Other examples from customers include:

“We got a detailed host cell protein overview and targeted elimination of impurities without developing a process-specific ELISA”

“We could compare and select the best-fitted ELISA assay, based on information of coverage of individual HCPs”

“By supplementing our ELISA with Alphalyse’s analysis, we could document key protein features, stability and process-related impurity levels of our anti-cancer drug”

“The results helped us optimize our process development, product quality and process-related impurities. Overall, we have saved at least $1.000.000 on antibodies and 1 year on our drug development so far”

Who will benefit from a free intro-meeting?

Our customers develop vaccines, therapeutic products, biosimilars, biopharmaceuticals or are consultants for such companies.

Our experience shows that you get the best results when 3-4 persons from your organization join the meeting.

Depending on the project, you should therefore invite the project manager and lead scientists from Analytical- or Process-Development.

Why rely on our expertise?

Our lab is the most experienced in the world for HCP analysis of biologics by Mass Spectrometry:

Our team of dedicated PhD-level experts spent 5 years developing and optimizing our HCP Analysis, in collaboration with leading experts in the field

We apply our analysis to all types of process samples and all types of expression systems, including CHO, E. coli, yeast etc.

To achieve robust results, we use the most advanced equipment on the market – and have completely automated the sample preparation

Recognized as an industry expert, we were invited give talks on HCP analysis at the last three BEBPA conferences and the recent Bioprocessing Summit

It’s FREE – all you invest is 1 hour of your time

Our goal is that you should end up SAVING time – our customers speed up their process development and optimize impurity removal using mass spectrometry based Host Cell Protein analysis.

Details:

Our HCP consultants are usually able to schedule a call with you and your team within a few days.
Before the meeting we will contact you to clarify, which parties you should involve at this early stage.

The meeting is conducted by phone or WebEx.

Our experience shows that you get the best results when 3-4 relevant persons from your organization participate.

During the meeting, we typically cover:

A summary of how the LC-MS analysis works

An introduction to your projects and challenges

A discussion of how you can benefit from including mass spectrometry in your HCP documentation

Still in doubt how you can benefit from a single hour with our experts?

Then consider this:

Do you want to AVOID project delays?

Are you in a hurry and would like to skip development of process specific HCP ELISA antibodies?

Would you like to intelligently remove HCPs based on information about pI and MW of individual HCPs?

We would love to set up a meeting to learn about your project and give you advice on how you can benefit from mass spectrometry based HCP analysis.