It was quite nerve-wracking to watch the SCIEX TripleTOFs get moved into the new labs. Since the regular staircase was too steep and long, we had to get them in through the fire-escape on the 1st floor! You can watch a video of it here >> We are now getting adjusted to the new surroundings… Read whole story
Our newly hired Inga Boll successfully defended her PhD on Friday 6 March. Inga thus became one of the last students who was allowed to defend their PhD at Syddansk Universitet – University of Southern Denmark – before it temporarily closed all activities in response to the COVID-19 pandemic that has now hit most of… Read whole story
In this newly published research article our scientists present a novel coverage method combining ELISA-based immunocapture with protein identification by liquid chromatography–tandem mass spectrometry (LC–MS/MS). Abstract Download article (open-access) >> Monitoring host cell proteins (HCPs) is one of the most important analytical requirements in production of recombinant biopharmaceuticals to ensure product purity and patient safety…. Read whole story
Two new members joined our team this week: Stine Thyssen (left) and Inga Boll (middle). We asked them what they anticipate the most, working at Alphalyse: “I look forward to using my expertise in protein chemistry to help our customers with their protein analysis. I am happy to be a part of Alphalyse where we… Read whole story
Soon, we’ll be moving our Headquarters to a new central location in Odense, Denmark with more than twice the amount of space – so we can expand our team and add even more instruments The builders just started the transformation, to make the building fit our needs – with state-of-the-art laboratories and open office space…. Read whole story
We seek two additional analytical protein scientists and a laboratory technician for our headquarters in Odense, Denmark to help develop analytical methods for protein characterization, and to perform analysis for our biopharma customers. Our most important asset is our team of highly skilled scientists, who are experts in characterization of biopharmaceutical proteins. Join our dedicated team… Read whole story
Whoop whoop!We won the BDO award for best digital transformation in the region of Southern Denmark! The award was accepted at a ceremony last week by a proud Thomas Kofoed (CEO at Alphayse) who said: “It was clear to us from day one that we had to digitalise our processes and we started with our… Read whole story
Join us in welcoming Christina Johannsen. She will be on secondment at Alphalyse for the next 2 months, and study quantitative methods for biologics. Christina joins Magdalena Sandberg in performing PhD research. Especially intact mass analysis and peptide mapping on a SCIEX X500b mass spectrometer. Thus, we plan to use their new methods for better… Read whole story
Reproducible sample preparation is perhaps the most important part of protein analysis. See how we managed to fully automate complex sample preparation for high reproducibility – and create a good work environment for our team using an Eppendorf Automation robot. Read article on Eppendorf website >>
The award was given because we have shown continues growth for the past 5 years. This has only been possible because of our loyal customers – in both North America and Europe. Thank you for your support! We promise to keep doing our best to help you expand your business – by providing you with… Read whole story
Your HCP analysis should be both reactive to broader populations of HCPs and more specific to HCPs likely to be in the final product. However, with current methods, based on 2D PAGE and Western Blot, it is difficult to know if both of these conditions are met. If you’re in Boston today, you can experience… Read whole story
For more than a decade, Alphalyse has been leading in protein ID services. Because we handle such a high volume, we now pass on the benefits to you. This means: We replace the MALDI analysis by LC-MS for even more accurate results – and faster turnaround if you have many samples. The Nanoflow LC-MS analysis is upgraded with an Evosep… Read whole story
BEBPA’s 7th annual Host Cell Protein Conference May 15-17th took place in Los Angeles, California. It once again attracted HCP experts from biopharma, service- and technology providers, and regulatory agencies. The organizing committee had again put together a great mix of talks, workshops and round-table discussions. Very importantly, there was also plenty of time for… Read whole story
CONGRATULATIONS to Katrine Pilely who Tuesday successfully defended her PhD thesis at the University of Copenhagen. Under supervision of Professor Peter Garred, Katrine Pilely studied how cholesterol crystals activate the immune system. This happens through complement-mediated mechanisms, and therefore contribute to the pathophysiology of atherosclerosis. Katrine further showed how to inhibit the upstream cholesterol crystal-induced… Read whole story
Magdalena joined Alphalyse back in April, when she came from a position at Genovis AB in Sweden. She takes part in the joint European PhD-fellowship program – also known as Analytics for Biologics (A4B). For her PhD project Magdalena now focuses on developing Multi Attribute Monitoring (MAM) LC-MS methods. Eventually, we will use these new methods… Read whole story
Friday we celebrated Sheila Maibom-Thomsen, who has conducted a PhD-study at the University of Southern Denmark. Sheila did her PhD research in cooperation with Alphalyse, developing novel approaches for characterization of biopharmaceutical monoclonal antibodies. Part of the project was done in collaboration with the Swedish company Genovis. As a result new enzymes for mAb analysis… Read whole story
Our skillful protein scientist, Anette Rasmussen, often goes the extra mile to help out our customers with their protein samples and questions related to protein analysis. Yesterday she showed great spirit when she ran a little over 9 miles (15 km) in the Staff Relay Race by DHL in Odense, to help out two of… Read whole story
Kerstin Poll from Sciex is teaching us how to get the most out of our new X500B QTOF. Soon we will be able to help you with new quantitative peptide maps by MAM. We will also be able to find variants of protein pharmaceuticals, and make even better analysis of product related impurities.
Not satisfied with your current protein analysis method? Let’s improve it! In this new article you get an example of how we invent new analysis and improve on existing methods in collaboration with our customers and suppliers – leading to cutting-edge LC-MS technology that specifically addresses your challenges. Labiotech.eu ►https://www.labiotech.eu/revealing-identity-hcp-sciex “It’s a perfect example of… Read whole story
Magdalena Widgren Sandberg just joined our team. She will participate in the joint European PhD-fellowship program known as A4B – Analytics for Biologics. The A4B project members work on improving therapeutic proteins. For example to improve on the production, purification, and analysis of therapeutic proteins. For her PhD project Magdalena will focus on Multi Attribute Monitoring… Read whole story