Intact protein mass analysis 0-250 kDa
Molecular weight determination by LC ESI-MS protein analysis is the golden standard for proteins up to 250 kDa. This technology provides very accurate MW data.
We load the protein sample onto an HPLC column and elute it off into the mass spectrometer. The advantage compared to MALDI-MS is the ability to analyze larger proteins. Also, the accuracy is higher by ESI-MS protein analysis.