Analysis of Host Cell Protein
9 articlesSimple way to perform label-free quantification of Host Cell Proteins
Question: I find it difficult to get an accurate label-free quantification of Host Cell Proteins with traditional multiple reaction monitoring using...
What is SWATH mass spectrometry and its advantages in HCP analysis?
Host Cell Proteins (HCPs) in protein biopharmaceuticals can be analyzed by the mass spectrometry SWATH analysis. It provides both identification...
Identification of small host cell proteins (small Mw HCPs)
Question: I work on a drug substance protein with a mass of 15 kDa. I would expect small host cell protein...
Host Cell Protein monitoring in process development – using mass spec
Mass spectrometry based Host Cell Protein identification and quantification The Mass Spec Host Cell Protein (HCP) assay is applied for monitoring...