Analysis of Host Cell Protein
8 articles
Can I use commercial HCP ELISA kits for FDA approval of clinical trial application?
Question: My company uses a commercial HCP ELISA kit for host cell protein analysis of clinical phase 1 material. We hear...
Simple way to perform label-free quantification of Host Cell Proteins
Question: I find it difficult to get an accurate label-free quantification of Host Cell Proteins with LC-MS. It also seems that my...
What is SWATH and why is it an advantage for Host Cell Protein analysis?
Host Cell Proteins (HCPs) in protein biopharmaceuticals can be analyzed by mass spectrometry - for both identification and quantification of...
Identification of small host cell proteins (low Mw HCPs)
Question: Could you suggest an analysis method to detect low Mw HCPs (small HCPs) below 20 kDa? I work on a drug...
Host Cell Protein monitoring & control in process development
Mass spectrometry based Host Cell Protein identification and quantification The Mass Spec Host Cell Protein (HCP) assay is applied for monitoring...