Analysis of Host Cell Protein
8 articles
Can I use commercial HCP ELISA kits for my clinical trial application?
Question: My company uses a commercial HCP ELISA kit for host cell protein analysis of clinical phase 1 material. We hear...
Simple way to perform label-free quantification of Host Cell Proteins
Question: I find it difficult to get an accurate label-free quantification of Host Cell Proteins with LC-MS. It also seems that my...
What is SWATH & why is it an advantage in Host Cell Protein analysis?
Host Cell Proteins (HCPs) in protein biopharmaceuticals can be analyzed by mass spectrometry - for both identification and quantification of...
Identification of small host cell proteins (low Mw HCPs)
Question: Could you suggest an analysis method to detect low Mw HCPs (small HCPs) below 20 kDa? I work on a drug...
Host Cell Protein monitoring & control in process development
Mass spectrometry based Host Cell Protein identification and quantification The Mass Spec Host Cell Protein (HCP) assay is applied for monitoring...